| 1. | Vertex Pharmaceuticals IncVRTX | BiotechnologyBiotechnology | 1,40,201.921,40,201.92 | 549.04549.04 | 32.2232.22 | 9.049.04 | 3.463.46 | 23.5423.54 | 7.007.00 | |
| 2. | Regeneron Pharmaceuticals IncREGN | BiotechnologyBiotechnology | 99,440.2999,440.29 | 930.67930.67 | 21.2521.25 | 28.1128.11 | -4.33-4.33 | 14.9514.95 | 2.872.87 | |
| 3. | Moderna IncMRNA | BiotechnologyBiotechnology | 88,163.2688,163.26 | 258.38258.38 | -- | 27.1527.15 | 13.1013.10 | -39.00-39.00 | 13.0913.09 | |
| 4. | argenx NV ADRARGX | BiotechnologyBiotechnology | 55,023.4255,023.42 | 901.12901.12 | 30.3130.31 | -1.29-1.29 | 3.363.36 | 23.6423.64 | 6.676.67 | |
| 5. | BeOne Medicines AGONC | BiotechnologyBiotechnology | 41,101.1441,101.14 | 377.78377.78 | 64.6364.63 | 4.464.46 | 6.416.41 | 14.6614.66 | 8.108.10 | |
| 6. | Revolution Medicines IncRVMD | BiotechnologyBiotechnology | 40,331.6840,331.68 | 199.70199.70 | -- | -3.84-3.84 | 2.742.74 | -79.09-79.09 | 15.7315.73 | |
| 7. | Royalty Pharma PlcRPRX | BiotechnologyBiotechnology | 38,437.6138,437.61 | 67.5667.56 | 35.3835.38 | 19.2419.24 | 1.741.74 | 13.9713.97 | 4.384.38 | |
| 8. | Genmab ASGMAB | BiotechnologyBiotechnology | 33,770.4433,770.44 | 55.5255.52 | 43.2443.24 | 44.2844.28 | -0.75-0.75 | 14.0014.00 | 5.895.89 | |
| 9. | Roivant Sciences LtdROIV | BiotechnologyBiotechnology | 25,924.1725,924.17 | 38.2338.23 | -- | 6.856.85 | 6.076.07 | -8.52-8.52 | 6.306.30 | |
| 10. | Incyte CorporationINCY | BiotechnologyBiotechnology | 24,468.0524,468.05 | 122.85122.85 | 61.2461.24 | 7.647.64 | 4.534.53 | 7.847.84 | 4.354.35 | |
| 11. | Insmed IncINSM | BiotechnologyBiotechnology | 23,980.4623,980.46 | 110.00110.00 | -- | 5.945.94 | 5.255.25 | -72.45-72.45 | 34.0134.01 | |
| 12. | BioNTech SEBNTX | BiotechnologyBiotechnology | 21,987.9221,987.92 | 86.9286.92 | -- | -10.98-10.98 | 4.334.33 | -9.30-9.30 | 1.121.12 | |
| 13. | Alnylam Pharmaceuticals IncALNY | BiotechnologyBiotechnology | 21,162.1421,162.14 | 159.89159.89 | 7.987.98 | -27.29-27.29 | 0.670.67 | 138.07138.07 | 6.136.13 | |
| 14. | Exelixis IncEXEL | BiotechnologyBiotechnology | 17,112.4817,112.48 | 72.3172.31 | 21.0021.00 | 22.8722.87 | 0.660.66 | 44.3244.32 | 9.239.23 | |
| 15. | Ascendis Pharma ASASND | BiotechnologyBiotechnology | 16,383.7916,383.79 | 250.17250.17 | 19.0819.08 | 9.719.71 | 3.313.31 | 118.78118.78 | 10.3210.32 | |
| 16. | Halozyme Therapeutics IncHALO | BiotechnologyBiotechnology | 14,635.5714,635.57 | 128.62128.62 | 37.7037.70 | 18.7518.75 | 1.331.33 | 173.67173.67 | 103.51103.51 | |
| 17. | BridgeBio Pharma IncBBIO | BiotechnologyBiotechnology | 14,609.0914,609.09 | 74.0374.03 | -- | 11.9311.93 | 5.305.30 | -1,789.67-1,789.67 | 123.68123.68 | |
| 18. | Jazz Pharmaceuticals PLCJAZZ | BiotechnologyBiotechnology | 13,920.2813,920.28 | 234.66234.66 | 63.4463.44 | -0.58-0.58 | 2.122.12 | 22.1122.11 | 2.922.92 | |
| 19. | Summit Therapeutics PLCSMMT | BiotechnologyBiotechnology | 11,806.6911,806.69 | 16.1716.17 | -- | -6.37-6.37 | 2.432.43 | -192.51-192.51 | 20.2920.29 | |
| 20. | Bio-Techne CorpTECH | BiotechnologyBiotechnology | 11,413.2311,413.23 | 72.7372.73 | 62.6562.65 | 0.210.21 | 0.100.10 | 9.039.03 | 5.415.41 | |