| 1. | Vertex Pharmaceuticals IncVRTX | BiotechnologyBiotechnology | 1,10,641.401,10,641.40 | 508.34508.34 | 29.9529.95 | -3.76-3.76 | -1.56-1.56 | 23.5423.54 | 6.446.44 | |
| 2. | Regeneron Pharmaceuticals IncREGN | BiotechnologyBiotechnology | 66,532.9566,532.95 | 784.85784.85 | 19.1619.16 | -3.13-3.13 | -0.62-0.62 | 14.0414.04 | 2.512.51 | |
| 3. | argenx NV ADRARGX | BiotechnologyBiotechnology | 51,218.6951,218.69 | 995.77995.77 | 37.5737.57 | 0.280.28 | -0.59-0.59 | 23.6423.64 | 7.287.28 | |
| 4. | Alnylam Pharmaceuticals IncALNY | BiotechnologyBiotechnology | 39,452.9739,452.97 | 245.51245.51 | 41.4841.48 | 7.397.39 | -2.46-2.46 | 96.5696.56 | 23.5523.55 | |
| 5. | Revolution Medicines IncRVMD | BiotechnologyBiotechnology | 32,469.8432,469.84 | 190.95190.95 | -- | -11.60-11.60 | -3.01-3.01 | -79.09-79.09 | 16.8816.88 | |
| 6. | BeiGene, Ltd.ONC | BiotechnologyBiotechnology | 31,378.5231,378.52 | 350.84350.84 | 62.1662.16 | -4.96-4.96 | -0.74-0.74 | 14.6614.66 | 7.587.58 | |
| 7. | Royalty Pharma PlcRPRX | BiotechnologyBiotechnology | 31,014.3231,014.32 | 58.4158.41 | 31.4431.44 | -2.14-2.14 | -0.85-0.85 | 13.9713.97 | 3.813.81 | |
| 8. | BioNTech SEBNTX | BiotechnologyBiotechnology | 23,644.6823,644.68 | 98.6698.66 | -- | 6.376.37 | -2.59-2.59 | -9.30-9.30 | 1.181.18 | |
| 9. | Insmed IncINSM | BiotechnologyBiotechnology | 23,062.4623,062.46 | 123.98123.98 | -- | -3.49-3.49 | -3.26-3.26 | -87.22-87.22 | 35.3435.34 | |
| 10. | Roivant Sciences LtdROIV | BiotechnologyBiotechnology | 21,427.0721,427.07 | 39.7739.77 | -- | 6.426.42 | -0.45-0.45 | -8.52-8.52 | 6.746.74 | |
| 11. | Incyte CorporationINCY | BiotechnologyBiotechnology | 19,398.8519,398.85 | 127.62127.62 | 15.5015.50 | 3.363.36 | -1.79-1.79 | 30.6730.67 | 3.893.89 | |
| 12. | Moderna IncMRNA | BiotechnologyBiotechnology | 18,660.8618,660.86 | 154.04154.04 | -- | 144.66144.66 | -2.57-2.57 | -39.00-39.00 | 8.498.49 | |
| 13. | Genmab ASGMAB | BiotechnologyBiotechnology | 16,398.1816,398.18 | 34.5334.53 | 26.8826.88 | 4.784.78 | 0.580.58 | 14.0014.00 | 3.523.52 | |
| 14. | Jazz Pharmaceuticals PLCJAZZ | BiotechnologyBiotechnology | 14,895.7714,895.77 | 243.84243.84 | 16.4716.47 | -3.65-3.65 | -1.24-1.24 | 22.1122.11 | 3.263.26 | |
| 15. | Ascendis Pharma ASASND | BiotechnologyBiotechnology | 14,699.5714,699.57 | 239.04239.04 | 19.1619.16 | -3.94-3.94 | -0.85-0.85 | 118.78118.78 | 9.479.47 | |
| 16. | BridgeBio Pharma IncBBIO | BiotechnologyBiotechnology | 13,537.9313,537.93 | 67.3167.31 | -- | -18.88-18.88 | -1.07-1.07 | -1,789.67-1,789.67 | 123.68123.68 | |
| 17. | Summit Therapeutics PLCSMMT | BiotechnologyBiotechnology | 13,318.9513,318.95 | 17.8517.85 | -- | 39.2439.24 | 0.730.73 | -192.51-192.51 | 22.0522.05 | |
| 18. | Ionis Pharmaceuticals IncIONS | BiotechnologyBiotechnology | 12,725.2212,725.22 | 46.7546.75 | -- | -21.57-21.57 | -4.95-4.95 | -105.50-105.50 | 17.8617.86 | |
| 19. | Exelixis IncEXEL | BiotechnologyBiotechnology | 12,562.7312,562.73 | 58.4958.49 | 17.9117.91 | 10.1110.11 | -0.26-0.26 | 44.3944.39 | 7.647.64 | |
| 20. | Madrigal Pharmaceuticals IncMDGL | BiotechnologyBiotechnology | 12,145.4912,145.49 | 531.52531.52 | -- | 1.361.36 | -0.55-0.55 | -53.31-53.31 | 23.1123.11 | |